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The trouble is that after a three week course of antibiotics most doctors will consider that the disease has been successfully treated regardless of presenting symptoms. To be clear, my recommendations are for so-called chronic Lyme disease. In other cases it may not, but it may make some improvements. Put two and two together and you quickly realize that there is no way to test to determine if a treatment has been successful other than the absence of symptoms. The current location opened in on 2. However, reportedly, not all cases of Lyme disease ever present these tell-tale symptoms. In a person who has been infected it is expected that the antibodies will continue to be present even after the infecting bacteria have been successfully killed.